apply_poppk

Function to apply saved population PK or PK-PD models to a
data frame of patient values.

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

apply_poppk function

<dl><dt>patient_df</dt>
<dd>Dataframe with patient covariate values. Must have
names used by model "mod"</dd>
<dt>mod</dt>
<dd>Population PK model to apply to rows of patient_df</dd>
<dt>...</dt>
<dd>Arguments passed on to population PK model.</dd></dl>

Arguments

Apply a population PK model to a data frame — apply_poppk

<dl>

<dt>patient_df</dt>
<dd>Dataframe with patient covariate values. Must have
names used by model "mod"</dd>


<dt>mod</dt>
<dd>Population PK model to apply to rows of patient_df</dd>


<dt>...</dt>
<dd>Arguments passed on to population PK model.</dd>

</dl>

apply_poppk: Apply a population PK model to a data frame

Description

Usage

Value

Arguments