create_intvl

Create a dosing schedule object with columns "infrt", "begin", "end" from
vectors of infusions and infusion end times. The argument "inittm" is used
to specify the starting time of the first infusion.

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

create_intvl function

<dl><dt>dose</dt>
<dd>Data frame with columns "time" and "infrt".</dd>
<dt>inittm</dt>
<dd>Starting time of initial infusion</dd></dl>

Arguments

dosing schedule
Create dosing schedule — create_intvl

<dl>

<dt>dose</dt>
<dd>Data frame with columns "time" and "infrt".</dd>


<dt>inittm</dt>
<dd>Starting time of initial infusion</dd>

</dl>

create_intvl: dosing schedule Create dosing schedule

Description

Usage

Value

Arguments