tci (version 0.1.2)

gen_eleveld_pd_pars: Eleveld model PD parameters

Description

Function to generate PD parameters for Eleveld model.

Usage

gen_eleveld_pd_pars(theta, eta, patient_vars)

Value

Numeric vector of PD parameters for Eleveld propofol model associated with a set of patient covariates.

Arguments

theta

Vector of fixed effects

eta

Vector of random effects

patient_vars

Named list of observed patient characteristics

Examples

data(eleveld_pd)
# PD fixed effect values and random effect variances from Eleveld et al. (2018)
eleveld_theta_pd_est <- c(3.08,0.146,93.0,1.47,8.03,0.0517,-0.00635,1.24,1.89)
eleveld_eta_pd_var <- c(0.242,0.702,0.230)
patient_covariates <- subset(eleveld_pd, ID == 403,
select = c("AGE","WGT","HGT","M1F2","PMA","TECH","A1V2"))
gen_eleveld_pd_pars(theta = eleveld_theta_pd_est,
                    eta = eleveld_eta_pd_var,
                    patient_vars = patient_covariates)