sigmoid_targetfn

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

sigmoid_targetfn function

<dl><dt>lpars</dt>
<dd>Logged parameter values</dd>
<dt>tms</dt>
<dd>Times to evaluate sigmoid function</dd>
<dt>bis0</dt>
<dd>BIS value with no drug administered</dd>
<dt>...</dt>
<dd>Arguments passed on to 'restrict_sigmoid' function</dd></dl>

Arguments

Sigmoid target function — sigmoid_targetfn

<dl>

<dt>lpars</dt>
<dd>Logged parameter values</dd>


<dt>tms</dt>
<dd>Times to evaluate sigmoid function</dd>


<dt>bis0</dt>
<dd>BIS value with no drug administered</dd>


<dt>...</dt>
<dd>Arguments passed on to 'restrict_sigmoid' function</dd>

</dl>

sigmoid_targetfn: Sigmoid target function

Description

Usage

Value

Arguments