tci_plasma

TCI algorithm based on the algorithm described by Jacobs (1990).

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

tci_plasma function

<dl><dt>Cpt</dt>
<dd>Target plasma concentration</dd>
<dt>pkmod</dt>
<dd>PK model</dd>
<dt>dtm</dt>
<dd>Duration of the infusion</dd>
<dt>maxrt</dt>
<dd>Maximum infusion rate. Defaults to 200 ml/min in reference to the
maximum infusion rate of 1200 ml/h permitted by
existing TCI pumps (e.g. Anestfusor TCI program).</dd>
<dt>cmpt</dt>
<dd>Compartment into which infusions are administered. Defaults to the first compartment.</dd>
<dt>...</dt>
<dd>Arguments passed on to pkmod.</dd></dl>

Arguments

TCI algorithm for plasma targeting — tci_plasma

<dl>

<dt>Cpt</dt>
<dd>Target plasma concentration</dd>


<dt>pkmod</dt>
<dd>PK model</dd>


<dt>dtm</dt>
<dd>Duration of the infusion</dd>


<dt>maxrt</dt>
<dd>Maximum infusion rate. Defaults to 200 ml/min in reference to the
maximum infusion rate of 1200 ml/h permitted by
existing TCI pumps (e.g. Anestfusor TCI program).</dd>


<dt>cmpt</dt>
<dd>Compartment into which infusions are administered. Defaults to the first compartment.</dd>


<dt>...</dt>
<dd>Arguments passed on to pkmod.</dd>

</dl>

tci_plasma: TCI algorithm for plasma targeting

Description

Usage

Value

Arguments

Examples