emax

Emax function. c50 is the concentration eliciting a 50
identifying the slope of the Emax curve at c50, E0 is the response value with no drug present,
Emx is the maximum effect size.

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

emax function

<dl><dt>ce</dt>
<dd>Vector of effect-site concentrations.</dd>
<dt>pars</dt>
<dd>Named vector of parameter values with names (c50,gamma,e0,emx).</dd></dl>

Arguments

Emax function — emax

<dl>

<dt>ce</dt>
<dd>Vector of effect-site concentrations.</dd>


<dt>pars</dt>
<dd>Named vector of parameter values with names (c50,gamma,e0,emx).</dd>

</dl>

emax: Emax function

Description

Usage

Value

Arguments

Examples