tci (version 0.2.0)

pkmod_eleveld_ppf: Eleveld population PK model for propofol

Description

Function takes patient covariate values required for the Eleveld PK or PK-PD model for propofol and returns a `pkmod` object with the appropriate model parameters.

Usage

pkmod_eleveld_ppf(
  AGE,
  TBW,
  HGT,
  MALE,
  OPIATE = TRUE,
  ARTERIAL = TRUE,
  PMA = NULL,
  PD = TRUE,
  ...
)

Value

`pkmod` object with Eleveld propofol population PK or PK-PD parameters

Arguments

AGE

Age (years)

TBW

Weight (kg)

HGT

Height (cm)

MALE

Sex, logical

OPIATE

Logical indicating presence of opiates. Defaults to TRUE.

ARTERIAL

PK based on arterial sampling rather than venous. Defaults to TRUE.

PMA

Post-menstrual age. Calculated as AGE + 40 weeks if not provided.

PD

Logical. Should PD parameters be returned in addition to PK parameters.

...

Arguments passed to `pkmod`

Examples

pkmod_eleveld_ppf(AGE = 40,TBW = 56,HGT=150,MALE = TRUE)