pkmod_kim

Evaluate Kim population PK model at patient covariate values.
Published in Kim et al. (2017). "Disposition of Remifentanil in Obesity: A New
Pharmacokinetic Model Incorporating the Influence of Body Mass"
Anesthesiology Vol. 126, 1019–1032. doi: https://doi.org/10.1097/ALN.0000000000001635

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Ryan Jarrett

Target Controlled Infusion (TCI)

pkmod_kim function

<dl><dt>AGE</dt>
<dd>Age (years)</dd>
<dt>TBW</dt>
<dd>Total body weight (kg).</dd>
<dt>HGT</dt>
<dd>Height (cm). Used to calculate BMI if BMI is not provided.</dd>
<dt>BMI</dt>
<dd>Body mass index. Used to calculate LBM if LBM is not provided.</dd>
<dt>MALE</dt>
<dd>Logical. Used to calculate LBM if LBM is not provided.</dd>
<dt>FFM</dt>
<dd>Fat-free mass. Can be used instead of BMI and MALE.</dd>
<dt>...</dt>
<dd>Arguments passed to `pkmod`</dd></dl>

Arguments

Kim population PK model for remifentanil — pkmod_kim

<dl>

<dt>AGE</dt>
<dd>Age (years)</dd>


<dt>TBW</dt>
<dd>Total body weight (kg).</dd>


<dt>HGT</dt>
<dd>Height (cm). Used to calculate BMI if BMI is not provided.</dd>


<dt>BMI</dt>
<dd>Body mass index. Used to calculate LBM if LBM is not provided.</dd>


<dt>MALE</dt>
<dd>Logical. Used to calculate LBM if LBM is not provided.</dd>


<dt>FFM</dt>
<dd>Fat-free mass. Can be used instead of BMI and MALE.</dd>


<dt>...</dt>
<dd>Arguments passed to `pkmod`</dd>

</dl>

pkmod_kim: Kim population PK model for remifentanil

Description

Usage

Value

Arguments

Examples