A data set containing 100 chemicals worth of data for the Tox21 assay
TOX21_ERa_BLA_Agonist_ratio, which measures response to estrogen receptor agonists.
The data can be accessed further through the Comptox Chemicals Dashboard
(<a href="https://comptox.epa.gov/dashboard">https://comptox.epa.gov/dashboard</a>).

datasets

The tcplfit2 R package performs basic concentration-response curve fitting. The original tcplFit() function in the tcpl R package performed basic concentration-response curvefitting to 3 models. With tcplfit2, the core tcpl concentration-response functionality has been expanded to process diverse high-throughput screen (HTS) data generated at the US Environmental Protection Agency, including targeted ToxCast, high-throughput transcriptomics (HTTr) and high-throughput phenotypic profiling (HTPP). tcplfit2 can be used independently to support analysis for diverse chemical screening efforts.

Jason Brown

tcplfit2

A Concentration-Response Modeling Utility

Thomas Sheffield

Richard S Judson

Sarah E. Davidson

Zhihui Zhao

Madison Feshuk

Katie Paul Friedman

mc3 function

An object of class <code>data.frame</code> with 32175 rows and 7 columns.

Format

A data set containing 100 chemicals worth of data for the Tox21 assay
TOX21_ERa_BLA_Agonist_ratio, which measures response to estrogen receptor agonists.
The data can be accessed further through the Comptox Chemicals Dashboard
(<a href='https://comptox.epa.gov/dashboard'>https://comptox.epa.gov/dashboard</a>).

mc3: Sample concentration-response data set from invitrodb

Description

Usage

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Format

Details