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texmexseq

Treatment Effect eXplorer for Microbial Ecology eXperiments that use sequence counts (aka texmexseq) is an R package designed to normalize OTU count data and correct for community composition changes that are common to a control and experimental unit.

How to use it

There is a demo of the code in the demo folder of the source distribution. The Example sections of the help pages for the functions in the package also have working commands.

Installation

The package in on CRAN, so it should be as easy as install.packages('texmexseq').

New in this version

Version 0.3 improved the behavior of z.transform.table and f.transform.table. It also resolved a conflict between dplyr and testthat.

Version 0.2 is a non-backward-compatible rework of version 0.1. The underlying theory and computational methods are the same. Rather than creating Pair and Quad functions, the transformations are made directly to the OTU tables. Plots are made using ggplot2, allowing easier manipulation and decoration. OTU tables are manipulated using dplyr, allowing easier filtering for interesting OTUs.

Acknowledgement

This package is mostly a rewording of the poilog package, designed to make it easier for microbial ecologists.

License

GPL-3

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Version

Install

install.packages('texmexseq')

Monthly Downloads

19

Version

0.3

License

GPL-3

Maintainer

Scott Olesen

Last Published

July 25th, 2016

Functions in texmexseq (0.3)

texmexseq-package

Treatment Effect eXplorer for Microbial Ecology eXperiments
z.transform.sample

transform from raw counts to Poisson-lognormal-based metrics
poilogMLE

maximum likelihood estimation for the Poisson lognormal
dpoilog

probability density function for the Poisson lognormal distribution
texmex.fit

wrapper for fitting the Poisson lognormal
quad.table

Create and plot ``quads'' of samples
ppplot

PP plot for Poisson lognormal distribution