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tileHMM (version 1.0-3)

Hidden Markov Models for ChIP-on-Chip Analysis

Description

This package provides methods and classes to build HMMs that are suitable for the analysis of ChIP-on-chip data. The provided parameter estimation methods include the Baum-Welch algorithm and Viterbi training as well as a combination of both.

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Version

Install

install.packages('tileHMM')

Monthly Downloads

1

Version

1.0-3

License

GPL (>= 2)

Maintainer

Peter Humburg

Last Published

September 29th, 2009

Functions in tileHMM (1.0-3)

logSum

Calculate log(x + y) from log(x) and log(y)
discDist-class

Class "discDist"
plot

Plotting of "contDist" Objects
initializeHMM-methods

Generate Objects of Class 'hmm'
region.position

Identify Enriched Regions
hmm.setup

Create HMM from Initial Parameter Estimates Obtained from Data
sampleSeq

Generate Observation Sequence from HMM
tileHMM-package

Hidden Markov Models for ChIP-on-Chip Analysis
internals

Internal Functions
baumWelch

Baum-Welch Algorithm
viterbi

Calculate Most Likely State Sequence Using the Viterbi Algorithm
viterbiEM

Efficient Estimation of HMM Parameters
region.length

Determine Length of Positive and Negative Regions
hmm-class

Class "hmm"
generate.data

Generate Simulated Dataset
states

State Names of Hidden Markov Model
viterbiTraining

Estimate HMM Parameters Using Viterbi Training
contHMM-access

Accessing Objects of Class "contHMM"
dist-access

Accessing and Converting Objects of Class "dist"
contDist-class

Class "contDist"
contHMM-class

Class "contHMM"
forward

Computation of Forward and Backward Variables
remove.short

Post-Processing of "tileHMM" Results
simChIP

Simulated ChIP-on-Chip Data
shrinkt.st

Calculate 'Shrinkage t' Statistic
getHMM

Create HMM from Parameter Values
tDist-class

Class "tDist"
gff2index

Extract Probe Calls from GFF File
reg2gff

Converting Information about Enriched Regions into GFF Format
dist-class

Class "dist"
initializeDist-methods

Generating Objects of Class 'dist'
posterior

Calculate Posterior Probability for States of HMM
sampleObs

Sample Observations from Probability Distribution