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tileHMM (version 1.0-4)

Hidden Markov Models for ChIP-on-Chip Analysis

Description

This package provides methods and classes to build HMMs that are suitable for the analysis of ChIP-on-chip data. The provided parameter estimation methods include the Baum-Welch algorithm and Viterbi training as well as a combination of both.

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Version

Install

install.packages('tileHMM')

Monthly Downloads

1

Version

1.0-4

License

GPL (>= 2)

Maintainer

Peter Humburg

Last Published

May 13th, 2011

Functions in tileHMM (1.0-4)

contDist-class

Class "contDist"
states

State Names of Hidden Markov Model
region.length

Determine Length of Positive and Negative Regions
sampleObs

Sample Observations from Probability Distribution
baumWelch

Baum-Welch Algorithm
getHMM

Create HMM from Parameter Values
reg2gff

Converting Information about Enriched Regions into GFF Format
shrinkt.st

Calculate 'Shrinkage t' Statistic
generate.data

Generate Simulated Dataset
posterior

Calculate Posterior Probability for States of HMM
remove.short

Post-Processing of "tileHMM" Results
dist-class

Class "dist"
simChIP

Simulated ChIP-on-Chip Data
sampleSeq

Generate Observation Sequence from HMM
plot

Plotting of "contDist" Objects
tileHMM-package

Hidden Markov Models for ChIP-on-Chip Analysis
viterbiEM

Efficient Estimation of HMM Parameters
tDist-class

Class "tDist"
internals

Internal Functions
hmm.setup

Create HMM from Initial Parameter Estimates Obtained from Data
discDist-class

Class "discDist"
gff2index

Extract Probe Calls from GFF File
viterbiTraining

Estimate HMM Parameters Using Viterbi Training
hmm-class

Class "hmm"
region.position

Identify Enriched Regions
contHMM-class

Class "contHMM"
initializeDist-methods

Generating Objects of Class 'dist'
forward

Computation of Forward and Backward Variables
contHMM-access

Accessing Objects of Class "contHMM"
initializeHMM-methods

Generate Objects of Class 'hmm'
logSum

Calculate log(x + y) from log(x) and log(y)
dist-access

Accessing and Converting Objects of Class "dist"
viterbi

Calculate Most Likely State Sequence Using the Viterbi Algorithm