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timeEL (version 0.9.1)

Freireich: Acute Leukemia data from Freireich et al (1963)

Description

In this study there were 21 pairs of subjects, and within each pair one subject received 6-mercaptopurine (6-MP) and one got placebo. The data are right censored. See also Gehan (1965) and Thomas & Grunkemeier (1975) who used the data as an illustrative example (ignoring the pairing).

Usage

Freireich

Arguments

Format

A data frame with 42 rows and 3 variables:

time

time in remission (in weeks)

status

event status, 1 is relapse, 0 is censored

group

treatment group: 0 (placebo) or 1 (6-MP)

References

Freireich et al (1963) Blood 21(6):699-716

Gehan (1965) Biometrika 52:203-223

Thomas & Grunkemeier (1975) JASA 70(352): 865-871