timma (version 1.2.0)

searchSpace: Generate search space

Description

A function to generate the search space for sffs

Usage

searchSpace(drug_number, k_set, profile_data, y_actual)

Arguments

drug_number

an integer to specify the number of drugs

k_set

a vector to specify the selected target set

profile_data

drug-target interaction data

y_actual

the drug sensitivity data

Value

• a list of the following components:
• IM_d
  search space of identical sets
• IM_superset
  search space of supersets
• IM_subset
  search space of subsets

Examples

data(tyner_interaction_binary)
data(tyner_sensitivity)
num<-length(tyner_sensitivity[,1])
k_set<-rep(0, dim(tyner_interaction_binary)[2])
k_set[1]<-1
space<-searchSpace(num, k_set, tyner_interaction_binary, tyner_sensitivity[,1])