Container class for parameters to fit the EffTox model in trialr.
efftox_params(real_doses, efficacy_hurdle, toxicity_hurdle, p_e, p_t, eff0,
tox1, eff_star, tox_star, alpha_mean, alpha_sd, beta_mean, beta_sd,
gamma_mean, gamma_sd, zeta_mean, zeta_sd, eta_mean, eta_sd, psi_mean, psi_sd)a vector of numbers.The doses under investigation. They should be ordered from lowest to highest and be in consistent units. E.g., to conduct a dose-finding trial of doses 10mg, 20mg and 50mg, use c(10, 20, 50).
Minimum acceptable efficacy probability. A number between 0 and 1.
Maximum acceptable toxicity probability. A number between 0 and 1.
Certainty required to infer a dose is acceptable with regards to being probably efficacious; a number between 0 and 1.
Certainty required to infer a dose is acceptable with regards to being probably tolerable; a number between 0 and 1.
Efficacy probability required when toxicity is impossible; a number between 0 and 1 (see Details).
Toxicity probability permitted when efficacy is guaranteed; a number between 0 and 1 (see Details).
Efficacy probability of an equi-utility third point (see Details).
Toxicity probability of an equi-utility third point (see Details).
The prior normal mean of the intercept term in the toxicity logit model. A number.
The prior normal standard deviation of the intercept term in the toxicity logit model. A number.
The prior normal mean of the slope term in the toxicity logit model. A number.
The prior normal standard deviation of the slope term in the toxicity logit model. A number.
The prior normal mean of the intercept term in the efficacy logit model. A number.
The prior normal standard deviation of the intercept term in the efficacy logit model. A number.
The prior normal mean of the slope term in the efficacy logit model. A number.
The prior normal standard deviation of the slope term in the efficacy logit model. A number.
The prior normal mean of the squared term coefficient in the efficacy logit model. A number.
The prior normal standard deviation of the squared term coefficient in the efficacy logit model. A number.
The prior normal mean of the association term in the combined efficacy-toxicity model. A number.
The prior normal standard deviation of the association term in the combined efficacy-toxicity model. A number.