trialr (version 0.0.7)

peps2_params: Parameters to be passed to BebopInPeps2 model in Stan

Description

The parameters required by the BebopInPeps2 Stan model are bundled up in a list, for convenience. This list contains elements that we might call "data" (e.g. trial outcomes), and "parameters" (e.g. modelling choices).

Value

A list with elements identified above.

Details

The list object has the following elements:

• J, Total number of patients used, positive integer.

• eff, a vector of logical values to represent the presence (=1) or absence (=0) of efficacy events in the patients.

• tox, a vector of logical values to represent the presence (=1) or absence (=0) of toxicity events in the patients.

• x1, a vector of logical values to represent whether the patients are pre-treated (=1) or treatment-naive (=0).

• x2, a vector of logical values to represent whether the patients are Low PD-L1 (=1) or not (=0).

• x3, a vector of logical values to represent whether the patients are Medium PD-L1 (=1) or not (=0). Logically, if x2 and x3 are both zero, then the patient is High PD-L1.

• cohort_n, vector of cohort sizes, provided for convenience.

• cohort_eff, vector of counts of efficacy events by cohort, provided for convenience.

• cohort_tox, vector of counts of toxicity events by cohort, provided for convenience.

• alpha_mean, The prior mean of alpha. Alpha is the efficacy model intercept.

• alpha_sd, The prior standard deviation of alpha. Alpha is the efficacy model intercept.

• beta_mean, The prior mean of beta. Beta is the efficacy model term for being previously treated.

• beta_sd, The prior standard deviation of beta. Beta is the efficacy model term for being previously treated.

• gamma_mean, The prior mean of gamma. Gamma is the efficacy model term for being PD-L1 score = Low.

• gamma_sd, The prior standard deviation of gamma. Gamma is the efficacy model term for being PD-L1 score = Low.

• zeta_mean, The prior mean of zeta. Zeta is the efficacy model term for being PD-L1 score = Medium.

• zeta_sd, The prior standard deviation of zeta. Zeta is the efficacy model term for being PD-L1 score = Medium.

• lambda_mean, The prior mean of lambda. Lambda is the toxicity model intercept.

• lambda_sd, The prior standard deviation of lambda. Lambda is the toxicity model intercept.

• psi_mean, The prior mean of psi. Psi is the joint model association parameter.

• psi_sd, The prior standard deviation of psi. Psi is the joint model association parameter.

An example of the peps2_params list is returned by peps2_get_data.

See Also

peps2_get_data