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trtswitch (version 0.1.6)

Treatment Switching

Description

Implements rank-preserving structural failure time model (RPSFTM), iterative parameter estimation (IPE), inverse probability of censoring weights (IPCW), and two-stage estimation (TSE) methods for treatment switching in randomized clinical trials.

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Install

install.packages('trtswitch')

Monthly Downloads

564

Version

0.1.6

License

GPL (>= 2)

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Repository

https://github.com/kaifenglu/trtswitch

Maintainer

Kaifeng Lu

Last Published

April 25th, 2025

Functions in trtswitch (0.1.6)

print.logisregr

Print logisregr Object

Parametric Regression Models for Failure Time Data

Proportional Hazards Regression Models

Logistic Regression Models for Binary Data

Log-Rank Test of Survival Curve Difference

QR Decomposition of a Matrix

Natural Cubic Spline Basis

Print phregr Object

Print liferegr Object

A simulated time-to-event data set with 10 replications

Brookmeyer-Crowley Confidence Interval for Quantiles of Right-Censored Time-to-Event Data

residuals_phregr

Residuals for Proportional Hazards Regression Models

Estimate of Restricted Mean Survival Time

The repeated measures data from the "Six Cities" study of the health effects of air pollution (Ware et al. 1984).

Survival Curve for Proportional Hazards Regression Models

Estimate of Restricted Mean Survival Time Difference

Urinary tract infection data from the logistf package

Rank Preserving Structural Failure Time Model (RPSFTM) for Treatment Switching

The randomized clinical trial SHIVA data in long format from the ipcwswitch package

splineDesigncpp

B-Spline Design Matrix

The Simple Two-Stage Estimation (TSE) Method for Treatment Switching

Simulate Survival Data for Two-Stage Estimation Method Using g-estimation

trtswitch-package

Treatment Switching

The Two-Stage Estimation (TSE) Method Using g-estimation for Treatment Switching

Split a survival data set at specified cut points

Tobin's tobit data from the survival package

Simulated CONCORDE trial data from the rpsftm package

B-Spline Basis for Polynomial Splines

Acute myelogenous leukemia survival data from the survival package

The binary data from Cox and Snell (1989, pp. 10-11).

Find Interval Numbers of Indices

Iterative Parameter Estimation (IPE) for Treatment Switching

Inverse Probability of Censoring Weights (IPCW) Method for Treatment Switching

Stanford heart transplant data from the survival package

Estimate of Milestone Survival Difference

Kaplan-Meier Estimates of Survival Curve