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tsdf

What is it?

tsdf calculates optimal Zhong's two-/three-stage Phase II designs, generates two-/three-stage Phase 1 dose finding decision table and allows user to run dose-finding simulations using customized decision table.

Installation

To install from CRAN:

install.packages("tsdf")

To install latest version from github :

install.packages("devtools")
devtools::install_github("wguo1990/tsdf")

References

[1] Bob Zhong, Single-arm phase IIA clinical trials with go/no-go decisions, 2012

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Version

Install

install.packages('tsdf')

Monthly Downloads

168

Version

1.1-8

License

GPL-2

Maintainer

Wenchuan Guo

Last Published

May 9th, 2020

Functions in tsdf (1.1-8)

print.opt.design

print Zhong's design from a "opt.design" object.
print.dec.table

print decision table from a "dec.table" object.
dec.table

generate three-stage dose-finding decision table
sl.sim

Dose-finding simulations for a list of scenarios
opt.design

Zhong's 2-/3- stage Phase II design
summary.dec.sim

Summarizing simulation results from a dec.sim object
plot.dec.sim

plot simulation results from a dec.sim object
plot.dec.table

plot decision table from a "dec.table" object.
adj.two

Zhong's 2-/3- stage Phase II design
dec.sim

run dose-finding simulations