calculate_objective

For a given set of system parameters the objective function
will be calculated based on defined cohorts and variance models.

internal

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

John Harrold

ubiquity

PKPD, PBPK, and Systems Pharmacology Modeling Tools

calculate_objective function

<dl><dt>parameters</dt>
<dd>system parameters</dd>
<dt>cfg</dt>
<dd>ubiquity system object</dd>
<dt>estimation</dt>
<dd>boolean variable to indicate if the objective function is being called during parameter estimation</dd></dl>

Arguments

Calculates the Value of the Specified Objective Function — calculate_objective

<dl>

<dt>parameters</dt>
<dd>system parameters</dd>


<dt>cfg</dt>
<dd>ubiquity system object</dd>


<dt>estimation</dt>
<dd>boolean variable to indicate if the objective function is being called during parameter estimation</dd>

</dl>

calculate_objective: Calculates the Value of the Specified Objective Function

Description

Usage

Value

Arguments