recompute_derived_biomarker_qc_flags

For the 61 composite biomarkers, 81 Nightingale biomarker ratios, and 76
extended biomarker ratios computed by <code>recompute_derived_biomarkers()</code>,
aggregates the biomarker QC flags from the underlying biomarkers
(see <code>nmr_info</code>).

A suite of utilities for working with the UK Biobank
<https://www.ukbiobank.ac.uk/> Nuclear Magnetic Resonance spectroscopy (NMR)
metabolomics data <https://biobank.ndph.ox.ac.uk/showcase/label.cgi?id=220>.
Includes functions for extracting biomarkers from decoded UK Biobank field
data, removing unwanted technical variation from biomarker concentrations,
computing an extended set of lipid, fatty acid, and cholesterol fractions,
and for re-deriving composite biomarkers and ratios after adjusting data
for unwanted biological variation. For further details on methods see
Ritchie SC et al. Sci Data (2023) <doi:10.1038/s41597-023-01949-y>.

Scott Ritchie

ukbnmr

Removal of Unwanted Technical Variation from UK Biobank NMR
Metabolomics Biomarker Data

recompute_derived_biomarker_qc_flags function

<dl><dt>x</dt>
<dd><code>data.frame</code> containing NMR metabolomics data from UK Biobank.
May either be raw field data output by
<a href="https://biobank.ctsu.ox.ac.uk/crystal/exinfo.cgi?src=accessing_data_guide">ukbconv</a>
or data with column names corresponding to biomarkers listed in <code>nmr_info</code>.</dd></dl>

Arguments

Aggregate QC Flags when recomputing all composite and derived biomarkers — recompute_derived_biomarker_qc_flags

<dl>

<dt>x</dt>
<dd><code>data.frame</code> containing NMR metabolomics data from UK Biobank.
May either be raw field data output by
<a href='https://biobank.ctsu.ox.ac.uk/crystal/exinfo.cgi?src=accessing_data_guide'>ukbconv</a>
or data with column names corresponding to biomarkers listed in <code>nmr_info</code>.</dd>

</dl>

recompute_derived_biomarker_qc_flags: Aggregate QC Flags when recomputing all composite and derived biomarkers

Description

Usage

Value

Arguments

Details

See Also

Examples