simulate_time_fixed

numeric value indicating the number of observations to be sampled.

npoints

numeric value indicating the maximum time point to include in the analysis.

censortime

subject id. Can be numeric or a character.

numeric identifier for each subject/model combination.

index

numeric value indicating the maximum number of data points collected from any subject.

max_datapoints

This function simulates observed timepoints for each subject according to a fixed sampling design.

Analyzes longitudinal data of HIV decline in patients on antiretroviral therapy using the canonical biphasic exponential decay model (pioneered, for example, by work in Perelson et al. (1997) <doi:10.1038/387188a0>; and Wu and Ding (1999) <doi:10.1111/j.0006-341X.1999.00410.x>). Model fitting and parameter estimation are performed, with additional options to calculate the time to viral suppression. Plotting and summary tools are also provided for fast assessment of model results.

simulate_time_fixed: Simulate timepoints for subjects according to fixed design.

Description

Usage

Arguments