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utr.annotation (version 1.0.4)

getTranscriptIdsForOneCodonVariant: Find the ensembl_transcript_id and codon postions for one variant

Description

Find the ensembl_transcript_id and codon postions for one variant

Usage

getTranscriptIdsForOneCodonVariant(
  variant,
  transcriptRegions,
  checkRegion,
  start,
  end
)

Arguments

variant

one row of variants table

transcriptRegions

transcripts structure table from ensembl

checkRegion

check if a transcript within a region stopCodon or startCodon

start

column name of the start region of checkRegion in transcripts structure table

end

column name of the end region of checkRegion in transcripts structure table

Value

A data table containing two columns: ensembl_transcript_id (id of transcripts for each variant which its mutation Pos is within those transcripts checkRegion.) codon_positions (positions of each nucleotides in the codon)

Details

For each variant, get all transcripts and extract their checkRegion's coordinates. For each transcript, check if the mutation Pos is within the region, if so, add that transcript's ensembl_transcript_id. If the mutation Pos is within multiple transcripts checkRegions, the transcripts ids are concatenate into one string with ";".