vcmeta (version 1.5.0)

meta.lc.mean2: Confidence interval for a linear contrast of mean differences from 2-group studies

Description

Computes the estimate, standard error, and confidence interval for a linear contrast of 2-group mean differences from two or more studies. A Satterthwaite adjustment to the degrees of freedom is used to improve the accuracy of the confidence interval. Equality of variances within or across studies is not assumed.

Usage

meta.lc.mean2(alpha, m1, m2, sd1, sd2, n1, n2, v)

Value

Returns 1-row matrix with the following columns:

• Estimate - estimated linear contrast

• SE - standard error

• LL - lower limit of the confidence interval

• UL - upper limit of the confidence interval

• df - degrees of freedom

Arguments

alpha

alpha level for 1-alpha confidence

m1

vector of estimated means for group 1

m2

vector of estimated means for group 2

sd1

vector of estimated SDs for group 1

sd2

vector of estimated SDs for group 2

n1

vector of group 1 sample sizes

n2

vector of group 2 sample sizes

v

vector of contrast coefficients

References

Bonett2009avcmeta

Examples

m1 <- c(45.1, 39.2, 36.3, 34.5)
m2 <- c(30.0, 35.1, 35.3, 36.2)
sd1 <- c(10.7, 10.5, 9.4, 11.5)
sd2 <- c(12.3, 12.0, 10.4, 9.6)
n1 <- c(40, 20, 50, 25)
n2 <- c(40, 20, 48, 26)
v <- c(.5, .5, -.5, -.5)
meta.lc.mean2(.05, m1, m2, sd1, sd2, n1, n2, v)

# Should return:
#          Estimate       SE       LL       UL       df
# Contrast     9.95 2.837787 4.343938 15.55606 153.8362