getWintimeIntegral_rest

This function calculates the win time difference integral for a single pair with truncation at time_restriction.
This function is used in all pairwise win time methods.

Performs an analysis of time-to-event clinical trial data using various "win time" methods,
including 'ewt', 'ewtr', 'rmt', 'ewtp', 'rewtp', 'ewtpr', 'rewtpr', 'max', 'wtr', 'rwtr', 'pwt', and 'rpwt'. These methods are used to calculate and compare
treatment effects on ordered composite endpoints. The package handles event times, event indicators, and treatment
arm indicators and supports calculations on observed and resampled data. Detailed explanations of each method and
usage examples are provided in "Use of win time for ordered composite endpoints in clinical trials," by Troendle et al.
(2024)<https://pubmed.ncbi.nlm.nih.gov/38417455/>. For more information, see the package documentation or the vignette titled "Introduction to wintime."

James Troendle

wintime

Win Time Methods for Time-to-Event Data in Clinical Trials

Samuel Lawrence

getWintimeIntegral_rest function

<dl><dt>m</dt>
<dd>The number of events in the hierarchy.</dd>
<dt>etimes</dt>
<dd>A sorted vector of event times (days) (returned from wintime::setEventTimes()).</dd>
<dt>time0</dt>
<dd>A vector containing the control person's event times (days).</dd>
<dt>time1</dt>
<dd>A vector containing the treatment person's event times (days).</dd>
<dt>delta0</dt>
<dd>A vector containing the control person's event indicators.</dd>
<dt>delta1</dt>
<dd>A vector containing the treatment person's event indicators.</dd>
<dt>time_restriction</dt>
<dd>The time restriction (days) for calculation.</dd></dl>

Arguments

Win time difference with time restriction — getWintimeIntegral_rest

<dl>

<dt>m</dt>
<dd>The number of events in the hierarchy.</dd>


<dt>etimes</dt>
<dd>A sorted vector of event times (days) (returned from wintime::setEventTimes()).</dd>


<dt>time0</dt>
<dd>A vector containing the control person's event times (days).</dd>


<dt>time1</dt>
<dd>A vector containing the treatment person's event times (days).</dd>


<dt>delta0</dt>
<dd>A vector containing the control person's event indicators.</dd>


<dt>delta1</dt>
<dd>A vector containing the treatment person's event indicators.</dd>


<dt>time_restriction</dt>
<dd>The time restriction (days) for calculation.</dd>

</dl>

getWintimeIntegral_rest: Win time difference with time restriction

Description

Usage

Value

Arguments