pProf

It plots estimated likelihood profile. This is not profile likelihood profile.

This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.

Kyun-Seop Bae

Minimization Tool for Pharmacokinetic-Pharmacodynamic Data
Analysis

pProf function

<dl> <dt>Bag</dt>
<dd>an environment or an object containing the objects of resultant environment e after nlr()</dd> <dt>Title</dt>
<dd>title for the plot</dd> <dt>...</dt>
<dd>arguments to pass to the plot function</dd></dl>

Arguments

Author

Plot Likelihood or Objective Fnnction Value Profile — pProf

<dl>

 <dt>Bag</dt>
<dd>an environment or an object containing the objects of resultant environment e after nlr()</dd>

 <dt>Title</dt>
<dd>title for the plot</dd>

 <dt>...</dt>
<dd>arguments to pass to the plot function</dd>

</dl>

pProf: Plot Likelihood or Objective Fnnction Value Profile

Description

Usage

Value

Arguments

Author

Details