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wrMisc (version 1.3.1)

Analyze Experimental High-Throughput (Omics) Data

Description

The efficient treatment and convenient analysis of experimental high-throughput (omics) data gets facilitated through this collection of diverse functions. Several functions address advanced object-conversions, like manipulating lists of lists or lists of arrays, reorganizing lists to arrays or into separate vectors, merging of multiple entries, etc. Another set of functions provides speed-optimized calculation of standard deviation (sd), coefficient of variance (CV) or standard error of the mean (SEM) for data in matrixes or means per line with respect to additional grouping (eg n groups of replicates). Other functions facilitate dealing with non-redundant information, by indexing unique, adding counters to redundant or eliminating lines with respect redundancy in a given reference-column, etc. Help is provided to identify very closely matching numeric values to generate (partial) distance matrixes for very big data in a memory efficient manner or to reduce the complexity of large data-sets by combining very close values. Many times large experimental datasets need some additional filtering, adequate functions are provided. Batch reading (or writing) of sets of files and combining data to arrays is supported, too. Convenient data normalization is supported in various different modes, parameter estimation via permutations or boot-strap as well as flexible testing of multiple pair-wise combinations using the framework of 'limma' is provided, too.

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Version

Install

install.packages('wrMisc')

Monthly Downloads

1,139

Version

1.3.1

License

GPL-3

Maintainer

Wolfgang Raffelsberger

Last Published

September 18th, 2020

Functions in wrMisc (1.3.1)

asSepList

Organize data as separate list-entries
buildTree

Connect edges to form tree and extract all possible branches
checkStrictOrder

Check for strict (ascencing or descending) order
convMatr2df

Convert matrix (eg with redundant) row-names to data.frame
convColorToTransp

Assign new transparency to given colors
checkSimValueInSer

Check for similar values in series
countSameStartEnd

Count same start- and end- sites of edges (or fragments)
exponNormalize

Normalize by adjusting exponent
exclExtrValues

Exclude extreme values (based on distance to mean)
filtSizeUniq

Filter for unique elements
cutArrayInCluLike

Cut 3-dim array in list of matrixes (or arrays) similar to organizing into clusters
filterList

Filter for unique elements
XYToDiffPpm

Express difference as ppm
addBeforFileExtension

Add text before file-extension
adjBy2ptReg

Linear rescaling of numeric vertor or matrix
arrayCV

CV of array
closeMatchMatrix

Reorganize results of search for close (similar) values in matrix-view
checkVectLength

Check length of vector
cleanReplicates

Replace most distant values by NA
completeArrLst

Complete list of arrays for same dimensions
cutAtMultSites

Cut character-vector at multiple sites
combineSingleT

Get all combinations with TRUE from each column
coinPermTest

Compare means of two vectors by permutation test
combineOverlapInfo

Find and combine points located very close in x/y space
combineByEitherFactor

Create factor-like column regrouping data regrouping simultaneaously by two factors
listBatchReplace

Replacements in list
listGroupsByNames

Organize values into list and sort by names
mergeSelCol

Merge selected columns out of 2 matrix or data.frames
mergeSelCol3

mergeSelCol3
cutToNgrp

Cut numeric vector to n groups (ie convert to factor)
nonAmbiguousMat

Transform matrix to non-ambiguous matrix (in respect to given column)
nonAmbiguousNum

make numeric vector non-ambiguous (ie unique)
correctWinPath

Correct mixed slash and backslash in file path
partialDist

Partial distance matrix (focus on closest)
elimCloseCoord

Eliminate close (overlapping) points (in x & y space)
readVarColumns

Read tabular content of files with variable number of columns
pasteC

Advanced paste-collapse
equLenNumber

Equal character-length number
rowGrpSds

Per line and per group sd-values
readXlsxBatch

Read batch of Excel xlsx-files
rowMedSds

sd of median for each row by bootstrap
countCloseToLimits

Count from two vectors number of values close within given limits
checkGrpOrderSEM

Check order of multiple groups including non-overlapping SEM-margins
checkGrpOrder

checkGrpOrder
firstOfRepeated

Find first of repeated elements
extrNumericFromMatr

Extract numeric part of matrix or data.frame
colMedSds

Standard error of median for each column by bootstrap
findSimilFrom2sets

Find similar numeric values from two vectors/matrixes
findUsableGroupRange

Select groups within given range
extrSpcText

Extract specific text
colSds

sd for each column
combineReplFromListToMatr

Combine replicates from list to matrix
convToNum

Convert to numeric
combineRedBasedOnCol

Combine/reduce redundant lines based on specified column
sortBy2CategorAnd1IntCol

Sort matrix by two categorical and one integer columns
correctToUnique

Correct vector to unique
fuseAnnotMatr

Fuse annotation matrix to initial matrix
extr1chan

Extract just one series, ie channel, of list of arrays
lmSelClu

Run lm on segmented data (from clustering)
lrbind

rbind on lists
stableMode

Estimate mode (most frequent value)
moderTestXgrp

Multiple moderated pair-wise t-tests from limma
moderTest2grp

Moderated pair-wise t-test from limma
nNonNumChar

Count number of non-numeric characters
firstLineOfDat

Filter matrix to keep only first of repeated lines
get1stOfRepeatedByCol

Get first of repeated by column
extrColsDeX

Flexible extraction of columns
firstOfRepLines

Reduce to first occurance of repeated lines
naOmit

Fast na.omit
ratioAllComb

Calculate all ratios between x and y
rankToContigTab

Contingenty tables for fit of ranking
getValuesByUnique

Print matrix-content as plot
matchNamesWithReverseParts

Value Matching with optional reversing of sub-parts of non-matching elements
triCoord

Pairwise x,y combinations
rowSds

sd for each row (fast execution)
replNAbyLow

Replace NAs by low values
replPlateCV

CV of replicate plates (list of matrixes)
treatTxtDuplicates

Locate duplicates in text and make non-redundant
rowSEMs

SEM for each row
transpGraySca

Make single vector gray-gradient
cbindNR

cbind to non-redundant
uniqCountReport

Report number of unique and redundant elements (optional figure)
checkAvSd

Check how multiple groups of data separate or overlap based on mean +/- sd
colorAccording2

Transform numeric values to color-gradient
contribToContigPerFrag

Characterize individual contribution of single edges in tree-structures
combinatIntTable

Planing for making all multiplicative combinations
extractLast2numericParts

Extract last two numeric parts from character vector
findCloseMatch

Find close numeric values between two vectors
diffCombin

Compute matrix of differences for all pairwise combinations of numeric vector
conv01toColNa

Convert matrix of integer to matrix of x-times repeated column-names
diffPPM

difference in ppm between numeric values
findRepeated

Find repeated elements
filt3dimArr

Filter a three-dimensional array of numeric data
writeCsv

Write (and convert) csv files
fuseCommonListElem

Fuse content of list-elements with redundant (duplicated) names
fusePairs

Fuse pairs to generate cluster-names
linRegrParamAndPVal

Fit linear regression, return parameters and p-values
makeNRedMatr

Make non-redundant matrix
organizeAsListOfRepl

(re)organize data of (3-dim) array as list of replicates
htmlSpecCharConv

Html special character conversion
makeMAList

make MA-List object
normalizeThis

Normalize data in various modes
presenceFilt

Filter lines of matrix for max number of NAs
randIndFx

Distance of categorical data (Jaccard,Rand and adjusted Rand index)
mergeW2

Extended version of merge for multiple objects (even without rownames)
minDiff

Minimum distance/difference between values
pVal2lfdr

Convert p-values to lfdr
nonredDataFrame

Filter for unique elements
nonRedundLines

Non-redundant lines of matrix
matr2list

Transform columns of matrix to list of vectors
partUnlist

Partial unlist of lists of lists
rmDupl2colMatr

Remove lines of matrix redundant /duplicated for 1st and 2nd column
rowCVs

rowCVs
nFragments

Number of fragments after cut at specific character(s) within size-range
nFragments0

Number of fragments after cut at specific character(s)
ratioToPpm

Convert ratio to ppm
renameColumns

Rename columns
regrMultBy1or2point

Rescaling of multiple data-sets according to reference data using regression
readCsvBatch

Read batch of csv-files
rowGrpCV

row group CV
reduceTable

Reduce table by aggregating smaller groups
rowGrpMeans

rowMeans with destinction of groups (of columns, eg groups of replicates)
stdErrMedBoot

Standard eror of median by boot-strap
sumNAperGroup

Count number of NAs per sub-set of columns
singleLineAnova

2-factorial Anova on single line of data
simpleFragFig

Simple figure showing line from start- to end-sites of edges (or fragments) defined by their start- and end-sites simpleFragFig draws figure showing start- and end-sites of edges (or fragments)
summarizeCols

Summarize columns (as median,mean,min,last or other methods)
tTestAllVal

t.test on all individual values against all other values
regrBy1or2point

Rescaling according to reference data using linear regression.
searchDataPairs

Search duplicated data over multiple columns, ie pairs of data
searchLinesAtGivenSlope

Search points forming lines at given slope
test2factLimma

2-factorial limma-style t-test
tableToPlot

Print matrix-content as plot
upperMaCoord

(upper) pairwise x,y combinations
withinRefRange

Check for values within range of reference