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wrMisc (version 1.4.2)

Analyze Experimental High-Throughput (Omics) Data

Description

The efficient treatment and convenient analysis of experimental high-throughput (omics) data gets facilitated through this collection of diverse functions. Several functions address advanced object-conversions, like manipulating lists of lists or lists of arrays, reorganizing lists to arrays or into separate vectors, merging of multiple entries, etc. Another set of functions provides speed-optimized calculation of standard deviation (sd), coefficient of variance (CV) or standard error of the mean (SEM) for data in matrixes or means per line with respect to additional grouping (eg n groups of replicates). Other functions facilitate dealing with non-redundant information, by indexing unique, adding counters to redundant or eliminating lines with respect redundancy in a given reference-column, etc. Help is provided to identify very closely matching numeric values to generate (partial) distance matrixes for very big data in a memory efficient manner or to reduce the complexity of large data-sets by combining very close values. Many times large experimental datasets need some additional filtering, adequate functions are provided. Batch reading (or writing) of sets of files and combining data to arrays is supported, too. Convenient data normalization is supported in various different modes, parameter estimation via permutations or boot-strap as well as flexible testing of multiple pair-wise combinations using the framework of 'limma' is provided, too.

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Version

Install

install.packages('wrMisc')

Monthly Downloads

1,139

Version

1.4.2

License

GPL-3

Maintainer

Wolfgang Raffelsberger

Last Published

November 20th, 2020

Functions in wrMisc (1.4.2)

checkAvSd

Check how multiple groups of data separate or overlap based on mean +/- sd
cleanReplicates

Replace most distant values by NA
convMatr2df

Convert matrix (eg with redundant) row-names to data.frame
convColorToTransp

Assign new transparency to given colors
cutAtMultSites

Cut character-vector at multiple sites
cutToNgrp

Cut numeric vector to n groups (ie convert to factor)
filt3dimArr

Filter a three-dimensional array of numeric data
extractLast2numericParts

Extract last two numeric parts from character vector
checkGrpOrderSEM

Check order of multiple groups including non-overlapping SEM-margins
checkGrpOrder

checkGrpOrder
checkSimValueInSer

Check for similar values in series
findSimilFrom2sets

Find similar numeric values from two vectors/matrixes
fuseCommonListElem

Fuse content of list-elements with redundant (duplicated) names
findUsableGroupRange

Select groups within given range
fusePairs

Fuse pairs to generate cluster-names
arrayCV

CV of array
adjBy2ptReg

Linear rescaling of numeric vertor or matrix
nonAmbiguousNum

make numeric vector non-ambiguous (ie unique)
combineRedBasedOnCol

Combine/reduce redundant lines based on specified column
combineReplFromListToMatr

Combine replicates from list to matrix
checkStrictOrder

Check for strict (ascencing or descending) order
buildTree

Connect edges to form tree and extract all possible branches
asSepList

Organize data as separate list-entries
combineByEitherFactor

Create factor-like column regrouping data regrouping simultaneaously by two factors
closeMatchMatrix

Reorganize results of search for close (similar) values in matrix-view
combineOverlapInfo

Find and combine points located very close in x/y space
coinPermTest

Compare means of two vectors by permutation test
countSameStartEnd

Count same start- and end- sites of edges (or fragments)
diffCombin

Compute matrix of differences for all pairwise combinations of numeric vector
nonRedundLines

Non-redundant lines of matrix
firstOfRepeated

Find first of repeated elements
fuseAnnotMatr

Fuse annotation matrix to initial matrix
cutArrayInCluLike

Cut 3-dim array in list of matrixes (or arrays) similar to organizing into clusters
addBeforFileExtension

Add text before file-extension
colMedSds

Standard error of median for each column by bootstrap
XYToDiffPpm

Express difference as ppm
partialDist

Partial distance matrix (focus on closest)
colSds

sd for each column
pasteC

Advanced paste-collapse
correctToUnique

Correct vector to unique
convToNum

Convert to numeric
contribToContigPerFrag

Characterize individual contribution of single edges in tree-structures
extr1chan

Extract just one series, ie channel, of list of arrays
readVarColumns

Read tabular content of files with variable number of columns
countCloseToLimits

Count from two vectors number of values close within given limits
exclExtrValues

Exclude extreme values (based on distance to mean)
correctWinPath

Correct mixed slash and backslash in file path
conv01toColNa

Convert matrix of integer to matrix of x-times repeated column-names
extrColsDeX

Flexible extraction of columns
get1stOfRepeatedByCol

Get first of repeated by column
combineSingleT

Get all combinations with TRUE from each column
colorAccording2

Transform numeric values to color-gradient
combinatIntTable

Planing for making all multiplicative combinations
diffPPM

difference in ppm between numeric values
rowGrpCV

row group CV
stdErrMedBoot

Standard eror of median by boot-strap
readXlsxBatch

Read batch of Excel xlsx-files
rowGrpMeans

rowMeans with destinction of groups (of columns, eg groups of replicates)
exponNormalize

Normalize by adjusting exponent
completeArrLst

Complete list of arrays for same dimensions
firstLineOfDat

Filter matrix to keep only first of repeated lines
htmlSpecCharConv

Html special character conversion
lrbind

rbind on lists
linModelSelect

Selecte best levels and plot linear regression model
makeMAList

make MA-List object
elimCloseCoord

Eliminate close (overlapping) points (in x & y space)
equLenNumber

Equal character-length number
findRepeated

Find repeated elements
findCloseMatch

Find close numeric values between two vectors
getValuesByUnique

Print matrix-content as plot
sumNAperGroup

Count number of NAs per sub-set of columns
firstOfRepLines

Reduce to first occurance of repeated lines
linRegrParamAndPVal

Fit linear regression, return parameters and p-values
listBatchReplace

Replacements in list
minDiff

Minimum distance/difference between values
matr2list

Transform columns of matrix to list of vectors
extrSpcText

Extract specific text
makeNRedMatr

Make non-redundant matrix
filterList

Filter for unique elements
filtSizeUniq

Filter for unique elements
extrNumericFromMatr

Extract numeric part of matrix or data.frame
matchNamesWithReverseParts

Value Matching with optional reversing of sub-parts of non-matching elements
mergeSelCol

Merge selected columns out of 2 matrix or data.frames
writeCsv

Write (and convert) csv files
listGroupsByNames

Organize values into list and sort by names
nFragments0

Number of fragments after cut at specific character(s)
lmSelClu

Run lm on segmented data (from clustering)
nNonNumChar

Count number of non-numeric characters
numPairDeColNames

Extract pair of numeric values from vector or column-names
normalizeThis

Normalize data in various modes
rankToContigTab

Contingenty tables for fit of ranking
nonredDataFrame

Filter for unique elements
organizeAsListOfRepl

(re)organize data of (3-dim) array as list of replicates
moderTestXgrp

Multiple moderated pair-wise t-tests from limma
moderTest2grp

Moderated pair-wise t-test from limma
nFragments

Number of fragments after cut at specific character(s) within size-range
ratioAllComb

Calculate all ratios between x and y
pVal2lfdr

Convert p-values to lfdr
naOmit

Fast na.omit
mergeSelCol3

mergeSelCol3
mergeW2

Extended version of merge for multiple objects (even without rownames)
nonAmbiguousMat

Transform matrix to non-ambiguous matrix (in respect to given column)
replNAbyLow

Replace NAs by low values
readCsvBatch

Read batch of csv-files
presenceFilt

Filter lines of matrix for max number of NAs
ratioToPpm

Convert ratio to ppm
replPlateCV

CV of replicate plates (list of matrixes)
searchDataPairs

Search duplicated data over multiple columns, ie pairs of data
reduceTable

Reduce table by aggregating smaller groups
rowSEMs

SEM for each row
rowSds

sd for each row (fast execution)
regrBy1or2point

Rescaling according to reference data using linear regression.
randIndFx

Distance of categorical data (Jaccard,Rand and adjusted Rand index)
triCoord

Pairwise x,y combinations
singleLineAnova

2-factorial Anova on single line of data
uniqCountReport

Report number of unique and redundant elements (optional figure)
rmDupl2colMatr

Remove lines of matrix redundant /duplicated for 1st and 2nd column
simpleFragFig

Simple figure showing line from start- to end-sites of edges (or fragments) defined by their start- and end-sites simpleFragFig draws figure showing start- and end-sites of edges (or fragments)
searchLinesAtGivenSlope

Search points forming lines at given slope
summarizeCols

Summarize columns (as median,mean,min,last or other methods)
partUnlist

Partial unlist of lists of lists
renameColumns

Rename columns
rowMedSds

sd of median for each row by bootstrap
regrMultBy1or2point

Rescaling of multiple data-sets according to reference data using regression
rowGrpSds

Per line and per group sd-values
withinRefRange

Check for values within range of reference
tTestAllVal

t.test on all individual values against all other values
upperMaCoord

(upper) pairwise x,y combinations
tableToPlot

Print matrix-content as plot
test2factLimma

2-factorial limma-style t-test
rowCVs

rowCVs
sortBy2CategorAnd1IntCol

Sort matrix by two categorical and one integer columns
transpGraySca

Make single vector gray-gradient
stableMode

Estimate mode (most frequent value)
treatTxtDuplicates

Locate duplicates in text and make non-redundant
cbindNR

cbind to non-redundant
checkVectLength

Check length of vector