Single Ascending Dose Data Set

Model generated PK data to mimic an orally administered small molecule. Simulated single dose administration ranging from 100 mg to 1600 mg.


A data frame with the following 16 columns:

column 1: ID numeric; unique subject ID
column 2: TIME numeric; time relative to first drug administration
column 3: NOMTIME numeric; nominal time
column 4: TIMEUNIT character; unit of TIME
column 5: AMT numeric; dosing amount (for dosing events) in mg
column 6: LIDV numeric; observation on a linear scale (observation type determined by CMT), units determined by EVENTU column
column 7: MDV numeric; missing dependent variable
(1 if missing, 0 otherwise) column 8: CMT
integer; compartment number (determines observation type):
CMT 1 = Dosing event
CMT 2 = PK concentration column 9: NAME
character; description of event column 10: EVENTU
character; unit for observation column 11: CENS
integer; censored values (0 = not censored, 1 = censored) column 12: EVID
integer; event ID (0 = observation, 1 = dosing event) column 13: WEIGHTB
numeric; baseline body weight (kg) column 14: SEX
character; sex column 15: TRTACT
factor; treatment group label column 1: ID

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Documentation reproduced from package xgxr, version 1.0.0, License: MIT + file LICENSE

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