nlmixr_theo_sd

<p>Theophylline dataset, from the nlmixr R package</p>

datasets

Supports a structured approach
for exploring PKPD data <https://opensource.nibr.com/xgx>. It also
contains helper functions for enabling the modeler to follow best R
practices (by appending the program name, figure name location, and
draft status to each plot). In addition, it enables the modeler to
follow best graphical practices (by providing a theme that
reduces chart ink, and by providing time-scale, log-scale, and
reverse-log-transform-scale functions for more readable axes).
Finally, it provides some data checking and summarizing functions for
rapidly exploring pharmacokinetics and pharmacodynamics (PKPD) datasets.

Andrew Stein

xgxr

Exploratory Graphics for Pharmacometrics

Alison Margolskee

Fariba Khanshan

Konstantin Krismer

Matthew Fidler

Novartis Pharma AG 

nlmixr_theo_sd function

<p>A data frame with the following 7 columns:</p><table><tr><td>
  column 1: </td>
<td> <code>ID</code> </td>
<td> integer; unique patient identifier</td>
</tr><tr><td>
  column 2: </td>
<td> <code>TIME</code> </td>
<td> numeric; time relative to first drug 
  administration</td>
</tr><tr><td>
  column 3: </td>
<td> <code>DV</code> </td>
<td> numeric; dependent variable (drug concentration) </td>
</tr><tr><td>
  column 4: </td>
<td> <code>AMT</code> </td>
<td> numeric; dose of drug </td>
</tr><tr><td>
  column 5: </td>
<td> <code>EVID</code> </td>
<td> integer; event ID, 1 if dose, 0 otherwise</td>
</tr><tr><td>
  column 6: </td>
<td> <code>CMT</code> </td>
<td> integer; compartment number</td>
</tr></table>

Format

nlmixr Theophylline SD Data Set — nlmixr_theo_sd

nlmixr Theophylline SD Data Set

nlmixr_theo_sd: nlmixr Theophylline SD Data Set

Description

Usage

Arguments

Format

column 1:	`ID`	integer; unique patient identifier
column 2:	`TIME`	numeric; time relative to first drug administration
column 3:	`DV`	numeric; dependent variable (drug concentration)
column 4:	`AMT`	numeric; dose of drug
column 5:	`EVID`	integer; event ID, 1 if dose, 0 otherwise
column 6:	`CMT`	integer; compartment number