mad_nca

<p>Multiple Ascending Dose Noncompartmental Analysis (NCA) dataset</p>

datasets

Supports a structured approach
for exploring PKPD data <https://opensource.nibr.com/xgx/>. It also
contains helper functions for enabling the modeler to follow best R
practices (by appending the program name, figure name location, and
draft status to each plot). In addition, it enables the modeler to
follow best graphical practices (by providing a theme that
reduces chart ink, and by providing time-scale, log-scale, and
reverse-log-transform-scale functions for more readable axes).
Finally, it provides some data checking and summarizing functions for
rapidly exploring pharmacokinetics and pharmacodynamics (PKPD) datasets.

Andrew Stein

xgxr

Exploratory Graphics for Pharmacometrics

Alison Margolskee

Fariba Khanshan

Konstantin Krismer

Matthew Fidler

Novartis Pharma AG 

mad_nca function

<p>A data frame with the following 7 columns:</p><table class="table">
<tr><td>column 1:</td><td><code>ID</code></td><td>numeric; unique subject ID</td></tr>
<tr><td>column 2:</td><td><code>PARAM</code></td><td>character; NCA parameter</td></tr>
<tr><td>column 3:</td><td><code>VALUE</code></td><td>numeric; Value of the NCA parameter</td></tr>
<tr><td>column 4:</td><td><code>DOSE</code></td><td>numeric; randomized dose in mg</td></tr>
<tr><td>column 15:</td><td><code>TRTACT</code></td><td>factor; treatment group label</td></tr>
<tr><td>column 14:</td><td><code>SEX</code></td><td>character; sex</td></tr>
<tr><td>column 13:</td><td><code>WEIGHTB</code></td><td>numeric; baseline body weight (kg)</td></tr>
</table><p></p><p></p>

Format

Multiple Ascending Dose Noncompartmental Analysis (NCA) dataset — mad_nca

<p>A data frame with the following 7 columns:</p><table class='table'>
<tr><td>column 1:</td><td><code>ID</code></td><td>numeric; unique subject ID</td></tr>
<tr><td>column 2:</td><td><code>PARAM</code></td><td>character; NCA parameter</td></tr>
<tr><td>column 3:</td><td><code>VALUE</code></td><td>numeric; Value of the NCA parameter</td></tr>
<tr><td>column 4:</td><td><code>DOSE</code></td><td>numeric; randomized dose in mg</td></tr>
<tr><td>column 15:</td><td><code>TRTACT</code></td><td>factor; treatment group label</td></tr>
<tr><td>column 14:</td><td><code>SEX</code></td><td>character; sex</td></tr>
<tr><td>column 13:</td><td><code>WEIGHTB</code></td><td>numeric; baseline body weight (kg)</td></tr>
</table>



mad_nca: Multiple Ascending Dose Noncompartmental Analysis (NCA) dataset

Description

Usage

Arguments

Format

column 1:	`ID`	numeric; unique subject ID
column 2:	`PARAM`	character; NCA parameter
column 3:	`VALUE`	numeric; Value of the NCA parameter
column 4:	`DOSE`	numeric; randomized dose in mg
column 15:	`TRTACT`	factor; treatment group label
column 14:	`SEX`	character; sex
column 13:	`WEIGHTB`	numeric; baseline body weight (kg)