xp_xtra example based on an nlmixr2 fitThis is the most basic one compartment example used in nlmixr2 example documentation. It is a fit to the popular theophylline dataset.
xpdb_nlmixr2xpdb_nlmixr2_saem
An object of class xp_xtras (inherits from xpose_data, uneval) of length 10.
An object of class xp_xtras (inherits from xpose_data, uneval) of length 10.
Fidler M (2025). nlmixr2: Nonlinear Mixed Effects Models in Population PK/PD. tools:::Rd_expr_doi("doi:10.32614/CRAN.package.nlmixr2"), R package version 3.0.2, https://CRAN.R-project.org/package=nlmixr2.
Fidler M, Wilkins J, Hooijmaijers R, Post T, Schoemaker R, Trame M, Xiong Y, Wang W (2019). "Nonlinear Mixed-Effects Model Development and Simulation Using nlmixr and Related R Open-Source Packages." CPT: Pharmacometrics & Systems Pharmacology, 8(9), 621-633. tools:::Rd_expr_doi("doi:10.1002/psp4.12445").
Schoemaker R, Fidler M, Laveille C, Wilkins J, Hooijmaijers R, Post T, Trame M, Xiong Y, Wang W (2019). "Performance of the SAEM and FOCEI Algorithms in the Open-Source, Nonlinear Mixed Effect Modeling Tool nlmixr." CPT: Pharmacometrics & Systems Pharmacology, 8(12), 923-930. tools:::Rd_expr_doi("doi:10.1002/psp4.12471").