This method initializes the Difference Filter.
The difference is the maximum value minus minimum value for each row of the expression dataframe
divided by the mean value of each row.
The Difference Filter flags all rows with: flag = ((max - min)/mean >= cutoff)
Usage
diffFilter(object)diffFilter(object, value)<-
Arguments
object
object of class PreFilter.
value
numeric vector c(cutoff, trim, epsilon).
Value
An initialized PreFilter object.
Details
The method diffFilter initializes the following parameters:
cutoff:
the cutoff level for the filter.
trim:
the trim value for trimmed mean (default is trim=0).
epsilon:
value to replace mean (default is epsilon=0.01):
epsilon > 0: replace mean=0 with epsilon.
Note, that for epsilon = 0 the filter flags all rows with: (max - min) >= cutoff