Learn R Programming

ZIBseq (version 1.2)

ZIBseq: Conducts the zero-inflated beta regression based on the general count data and categorical vector outcome.

Description

zero-inflated beta regression

Usage

ZIBseq(data, outcome, transform = F, alpha = 0.05)

Arguments

data

a matrix records the count data

outcome

a categorical vector of a specific kind of clinical condition

transform

square-root transform of the compositional matrix

alpha

customized threshold while calculating q values

Value

sigFeature

output the significant feature

useFeature

features being concerned

qvalue

qvalue

pvalue

pvalue

%% ...

Details

The function takes the sparse nature of metagenomics data into account and handle the compositional data efficiently.

References

Peng Xiaoling, Li Gang, and Liu Zhenqiu. Journal of Computational Biology. January 2016, 23(2): 102-110. doi:10.1089/cmb.2015.0157.

See Also

calc_qvalues