data and categorical vector outcome.
zero-inflated beta regression
ZIBseq(data, outcome, transform = F, alpha = 0.05)a matrix records the count data
a categorical vector of a specific kind of clinical condition
square-root transform of the compositional matrix
customized threshold while calculating q values
output the significant feature
features being concerned
qvalue
pvalue
The function takes the sparse nature of metagenomics data into account and handle the compositional data efficiently.
Peng Xiaoling, Li Gang, and Liu Zhenqiu. Journal of Computational Biology. January 2016, 23(2): 102-110. doi:10.1089/cmb.2015.0157.