AGDEX (version 1.18.0)

mouse.data: Mouse Data

Description

mouse.data is an ExpressionSet object where exprs slot carries the mouse gene expression data and pData carries the phenotype data.

Usage

data(mouse.data)

Value

expr(mouse.data)

A matrix with 264 rows and 192 columns with rows representing probe-sets and cloumns of mouse sample IDs. Each row name of the matrix is a probe-set Identifier.

pData(mouse.data)

A data frame with 192 rows and 2 columns. Each row represents one mouse sample. Column id is the mouse sample ID and grp is the assigned sample group label.

Details

This mouse.data is a subset taken from our published mouse data (Johnson et al. 2010). The original full mouse data was profiled by affymetrix 430 v2(mRNA). It contains 45037 probe-sets for 13 mice brain tumors and 179 normal mice stem cells. We used the best-match data (available from www.affymetrix.com) as the mapping data of ortholog-matched probe-sets across human gene expression data and mouse gene expression data. expr slot of mouse.data is a matrix of subset of the full mouse gene expression data. Those selected mouse probe-sets are ortholog-matched with human probe-sets in human.data. pData slot of the mouse.data is a data frame with row representing mouse samples and two columns indicating sample IDs and sample group labels for each sample (either "mouse.tumor" or "mouse.control").

References

R. Johnson et al.(2010) Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature, 466: 632-6.

See Also

ExpressionSet-class

agdex; human.data; map.data; gset.data

Examples

data(mouse.data)
mouse.express.set <- exprs(mouse.data)
mouse.pheno.data <- pData(mouse.data)