Print method for a 3+3 design specified using a threep3.
# S3 method for threep3
print(x, tox.cutpoints = NULL, dose = NULL, ...)An object of class "threep3" as returned by threep3
An optional argument passed to print.threep3
specifying the cutpoints of toxicity for which the operating characteristics
are to be categorised. Defaults to seq(from=0, to=1, by=0.2)
Optional vector of length k of actual doses for
presentation purposes
Further arguments passed to or from other methods
The following operating characteristics are printed for the standard 3+3 design:
Mean, minimum and maximum sample size of the design
Proportion of patients recruited to each dose, and to each true region of toxicity, on average
Proportion of 3+3 trials that would
recommend each of the dose levels as the final maximum tolerated dose (see
threep3 for definition of the MTD), and the associated regions
of true toxicity for the recommended MTDs
The average number of patients dosed at each level
The average number of DLTs seen at each level
Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1--26. http://www.jstatsoft.org/article/view/v054i13