<p>A matrix of hidden transcription factr activity estimated from gene expression data, with transcription factrs as rows and samples as columns.</p>

Prior transcription factor binding knowledge and target gene expression data are integrated in a Bayesian framework for functional cis-regulatory module inference. Using Gibbs sampling, we iteratively estimate transcription factor associations for each gene, regulation strength for each binding event and the hidden activity for each transcription factor.

Xi Chen

BICORN

Integrative Inference of De Novo Cis-Regulatory Modules

X: Transcription factr activity matrix

Description

Usage

Arguments

Format