BICORN (version 0.1.0)

sigmanoise_sampling: Fitting Residule Variance Sampling Function

Description

Function 'sigmanoise_sampling' estimates the variance of overal gene expression fitting residuals, according to an inverse-gamma distribution.

Usage

sigmanoise_sampling(Y, C, A, X, base_line, C_prior, sigma_A, sigma_baseline,
  sigma_X, alpha, beta)

Arguments

Y

gene expression data matrix

C

sampled TF-gene binding network

A

sampled regulatory strength matrix

X

sampled transcription factor activity matrix

base_line

sampled gene expression baseline activity

C_prior

prior TF-gene binding network

sigma_A

variance of regulatory strength

sigma_baseline

variance of gene expression baseline activity

sigma_X

variance of transcription factor activity

alpha

hyper-parameter for inverse-gamma distribution

beta

hyper-parameter for inverse-gamma distribution