HLA_data

A synthetic dataset of HLA genotypes for using bigdawg.

datasets

Data sets and functions for chi-squared Hardy-Weinberg and case-
    control association tests of highly polymorphic genetic data [e.g., human
    leukocyte antigen (HLA) data]. Performs association tests at multiple levels of
    polymorphism (haplotype, locus and HLA amino-acids). Combines rare variants to
    a common class to account for sparse cells in tables as described by Hollenbach
    JA, Mack SJ, Thomson G, Gourraud PA. 'Analytical methods for disease association
    studies with immunogenetic data.' Methods Mol Biol. 2012;882:245-66.

Steve Mack

BIGDAWG

Case-Control Analysis of Multi-Allelic Loci

HLA_data function

A data frame with 2000 rows and 14 variables:

HLA_data: Example HLA Dataset

Description

Usage

Arguments

format