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BIGDAWG (version 1.2.8)
Case-Control Analysis of Multi-Allelic Loci
Description
Data sets and functions for chi-squared Hardy-Weinberg and case-control
association tests of highly polymorphic genetic data [e.g., human leukocyte antigen
(HLA) data]. Performs association tests at multiple levels of polymorphism
(haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach
JA, Mack SJ (2016) . Combines rare variants to a
common class to account for sparse cells in tables as described by Hollenbach JA,
Mack SJ, Thomson G, Gourraud PA (2012) .