DRB345.Check.Wrapper

Row of data set data frame following DRB345 parsing

Genotype

DRBx Loci of interest to test for consistency

Loci.DR

Checks DR haplotypes for correct zygosity and flags unanticipated haplotypes

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

DRB345.Check.Wrapper: DRB345 haplotype zygosity wrapper

Description

Usage

Arguments