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BUS (version 1.28.0)

BUS-package: For network reconstruction.

Description

This package can be used to compute associations among genes (gene-networks) or between genes and some external traits (i.e. clinical). [Function: BUS]

Both associations can be computed via correlation or mutual information (MI). [Functions: gene.similarity (gene-gene associations) and gene.trait.similarity (gene-trait associations)]

Statistical significance of the association is computed for single and multiple hypotheses testing, using random permutations method [Functions: gene.pvalue, gene.trait.pvalue]

The package can handle data with missing values using bootstrapping methods to fill NAs. [Arguments: na.replica]

Arguments

Details

Package:
BUS
Type:
Package
Version:
1.0.2
Date:
2009-10-31
License:
GPL-3