Calculate marginal probability of observed genotypes under 'pathogenic region' model
lower_bound_P_v_by_direct_sum
Calculate marginal probability of observed genotypes under variant-level pathogenicity model by summing over marginals condintional on pathogenic variant combinations
Calculate region or variant-level probability of pathogencity given prior probability on pathogenicity of region
Concatenate objects of class BeviMed
R interface to BeviMed c++ MCMC procedure
Calculate marginal probability of observed genotypes under variant-level pathogenicity model
Apply the MCMC algorithm in blocks until conditions are met
Perform inference under model variant-level model v for y using MCMC sampling
Generate samples from the posterior under the variant-level pathogenicity model
Tune temperatures using interval bisection to minimimise Kullback-Liebler divergence between adjacent power posteriors
Calculate marginal probability of observed genotypes under 'null' model
A short title line describing what the package does
Print readable summary of BeviMed_summary object.
Calculate log Bayes factor comparing the variant-level model for case-control status
estimate_confidence_interval
Estimate confidence interval for estimated marginal likelihood by simulation
Calculate the Marginal Likelihood under v by summation over power posterior likelihood exptectances
Print readable summary of BeviMed object.
Tune the proposal standard deviations for the Metropolis-Hastings updates of either phi or omega
Create summary of BeviMed classed-object