⚠️There's a newer version (2.3) of this package.Take me there.

BiSEp (version 2.2)

Toolkit to Identify Candidate Synthetic Lethality

Description

Enables the user to infer potential synthetic lethal relationships by analysing relationships between bimodally distributed gene pairs in big gene expression datasets. Enables the user to visualise these candidate synthetic lethal relationships.

Copy Link

Version

Install

install.packages('BiSEp')

Monthly Downloads

216

Version

2.2

License

Artistic-2.0

Maintainer

Mark Wappett

Last Published

January 26th, 2017

Functions in BiSEp (2.2)

BEEM

BEEM: Bimodal Expression Exclusive with Mutation

MUT_data

A matrix containing discreet mutation calls

waterfallPlot

waterfallPlot: Create visualisations from BEEM output

BISEP_dat

A list object containing 3 data frames.

BiSEp-package

BiSEp: Bimodality in gene expression to dissect tumours and reveal synthetic lethal drug targets and biomarkers

BIGEE

BIGEE: Bimodal Gene Expression Exclusivity.

FURE_data

Output matrix from the BIGEE tool

INPUT_data

A Log2 Gene Expression matrix

expressionPlot

expressionPlot: Create visualisations from BIGEE output

BISEP_data

A list object containing 3 data frames.

FURE

FURE: Functional redundancy between synthetic lethal gene pairs

BISEP

BISEP: Bimodality in Gene Expression data.