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BiSEp (version 2.2)
Toolkit to Identify Candidate Synthetic Lethality
Description
Enables the user to infer potential synthetic lethal relationships by analysing relationships between bimodally distributed gene pairs in big gene expression datasets. Enables the user to visualise these candidate synthetic lethal relationships.
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Version
Version
2.2
2.0.1
1.0
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Install
install.packages('BiSEp')
Monthly Downloads
246
Version
2.2
License
Artistic-2.0
Maintainer
Mark Wappett
Last Published
January 26th, 2017
Functions in BiSEp (2.2)
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BEEM
BEEM: Bimodal Expression Exclusive with Mutation
MUT_data
A matrix containing discreet mutation calls
waterfallPlot
waterfallPlot: Create visualisations from BEEM output
BISEP_dat
A list object containing 3 data frames.
BiSEp-package
BiSEp: Bimodality in gene expression to dissect tumours and reveal synthetic lethal drug targets and biomarkers
BIGEE
BIGEE: Bimodal Gene Expression Exclusivity.
FURE_data
Output matrix from the BIGEE tool
INPUT_data
A Log2 Gene Expression matrix
expressionPlot
expressionPlot: Create visualisations from BIGEE output
BISEP_data
A list object containing 3 data frames.
FURE
FURE: Functional redundancy between synthetic lethal gene pairs
BISEP
BISEP: Bimodality in Gene Expression data.