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Biopeak (version 1.0)

Identification of Impulse-Like Gene Expression Changes in Short Genomic Series Data

Description

Enables the user to systematically identify and visualize impulse-like gene expression changes within short genomic series experiments. In order to detect such activation peaks, the gene expression is treated as a signal that propagates along an experimental axis (time, temperature or other series conditions). Peaks are selected by exhaustive identification of local maximums and subsequent filtering based on a range of controllable parameters. Moreover, the 'Biopeak' package provides a series of data exploration tools including: expression profile plots, correlation heat maps and clustering functionalities.

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Version

Install

install.packages('Biopeak')

Monthly Downloads

22

Version

1.0

License

GPL (>= 2)

Maintainer

David Lauenstein

Last Published

August 21st, 2019

Functions in Biopeak (1.0)

plotExpression

Plot the expression signal of individual genes
findPeaks

Identification of peaks in an expression signal
plotHeatmap

Plot a heatmap for selected genes
maProcessing

Pre-processing of microarray datasets
bgCorr

Background noise correction of expression data
saveOutput

Save the peak detection output to a text file
peakDetection

Identification of biomarkers specific to distinct phases of the underlying biological process
findClusters

Identification of clusters with similar temporal regulation
heat

Transcriptional profiles of human epithelial cells in response to heat
getCormat

Identification of co-expressing genes