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CLONETv2 (version 2.2.1)

Clonality Estimates in Tumor

Description

Analyze data from next-generation sequencing experiments on genomic samples. 'CLONETv2' offers a set of functions to compute allele specific copy number and clonality from segmented data and SNPs position pileup. The package has also calculated the clonality of single nucleotide variants given read counts at mutated positions. The package has been developed at the laboratory of Computational and Functional Oncology, Department of CIBIO, University of Trento (Italy), under the supervision of prof Francesca Demichelis. References: Prandi et al. (2014) ; Carreira et al. (2014) ; Romanel et al. (2015) .

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Install

install.packages('CLONETv2')

Monthly Downloads

252

Version

2.2.1

License

MIT + file LICENSE

Maintainer

Yari Ciani

Last Published

October 13th, 2021

Functions in CLONETv2 (2.2.1)

pl_table_toy

Toy example of ploidy table.
compute_scna_clonality_table

Function to compute clonality of somatic copy number data
snv_clonality_table_toy

Toy example of snv clonality table.
compute_ploidy

Function to compute ploidy from a beta table.
seg_tb_toy

Toy example of segmetd data.
compute_beta_table

Function to compute beta table
compute_snv_clonality

Function to compute clonality of SNVs
compute_dna_admixture

Function to compute DNA admixture of a tumor sample from the associatd beta table and ploidy table
scna_clonality_table_toy

Toy example of clonality table of somatic copy number.
error_table

Beta estimation error.
check_ploidy_and_admixture

Function to compute ploidy from a beta table.
compute_allele_specific_scna_table

Function to compute allele specific somatic copy number
bt_toy

Toy example of beta table.
allele_specific_cna_table_toy

Toy example of allele specific table of somatic copy number.
snv_reads_toy

Toy example of snv data.
CLONETv2-package

CLONETv2
adm_table_toy

Toy example of admixture table.
pileup_normal_toy

Toy example of normal pileup data.
pileup_tumor_toy

Toy example of tumor pileup data.