CausalR (version 1.4.3)

GetRegulatedNodes: get regulated nodes

Description

This function will compute the nodes regulated by the given hypothesis gene and write the results to a file

Usage

GetRegulatedNodes(PPInet, Expressiondata, delta, hypothesisGene = "", signOfHypothesis = 1, outputfile = "")

Arguments

PPInet

a protein-protein interaction network

Expressiondata

a table of observed gene expression data

delta

the number of edges to follow along the network. This should typically be between 1 and 5 dependent on network size/topology

hypothesisGene

the name of the hypothesis gene

signOfHypothesis

the sign of action expected from the hypothesis, +1 for up regulation, -1 for down

outputfile

the file to which the results should be written

Value

Nodes regulated by hypothesis gene