methotrexate

Methotrexate is a drug used totreat cancer, but there is concern that it may itself be carcinogenic in healthy individuals who are exposed while either manufacturing or administering the drug.
Deng et al. (2005) compared 21 workers engaged in the production of methotrexate to 21 unexp osed controls matched for age, gender, and smoking. The variables are (prefix &quot;w&quot; means exposed and &quot;c&quot; means control)
<dl class="dl-horizontal">
<dt>Mftcr</dt><dd>mutant frequency of TCR gene</dd>
<dt>Mfhrpt</dt><dd>mutant frequency of hprt gene</dd>
<dt>mtl</dt><dd>mean tail length</dd>
<dt>mtm</dt><dd>mean tail moment</dd>
<dt>id</dt><dd>identifier</dd>
<dt>sex</dt><dd>sex</dd>
<dt>age</dt><dd>age</dd>
<dt>smoke</dt><dd>smoking</dd>
<dt>years</dt><dd>exposure years</dd>
<dt>protection</dt><dd>protection measures, G for gloves, M for mask, N for none</dd>
<dt>mask</dt><dd>if the protection includes mask</dd>
</dl>

datasets

Cross-screening is a new method that uses both random halves of the sample to screen and test many hypotheses. It generally improves statistical power in observational studies when many hypotheses are tested simultaneously. References: 1. Qingyuan Zhao, Dylan S Small, and Paul R Rosenbaum. Cross-screening in observational studies that test many hypotheses. <arXiv:1703.02078>. 2. Qingyuan Zhao. On sensitivity value of pair-matched observational studies. <arXiv:1702.03442>.

Qingyuan Zhao

CrossScreening

Cross-Screening in Observational Studies that Test Many
Hypotheses

Paul Rosenbaum

methotrexate function

Format

Methotrexate is a drug used totreat cancer, but there is concern that it may itself be carcinogenic in healthy individuals who are exposed while either manufacturing or administering the drug.
Deng et al. (2005) compared 21 workers engaged in the production of methotrexate to 21 unexp osed controls matched for age, gender, and smoking. The variables are (prefix &quot;w&quot; means exposed and &quot;c&quot; means control)
<dl class='dl-horizontal'>
<dt>Mftcr</dt><dd>mutant frequency of TCR gene</dd>
<dt>Mfhrpt</dt><dd>mutant frequency of hprt gene</dd>
<dt>mtl</dt><dd>mean tail length</dd>
<dt>mtm</dt><dd>mean tail moment</dd>
<dt>id</dt><dd>identifier</dd>
<dt>sex</dt><dd>sex</dd>
<dt>age</dt><dd>age</dd>
<dt>smoke</dt><dd>smoking</dd>
<dt>years</dt><dd>exposure years</dd>
<dt>protection</dt><dd>protection measures, G for gloves, M for mask, N for none</dd>
<dt>mask</dt><dd>if the protection includes mask</dd>
</dl>

methotrexate: Methotrexate workers

Description

Usage

Arguments

Format

References