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DBGSA (version 1.1)

DBGSA-package: methods of distance-based gene set functional enrichment analysis

Description

DBGSA package provides a new method to evaluate the possiblities of the enrichment between different phenotypes. DBGSA is a novel distance-based gene set enrichment analysis method. We consider that, the distance between 2 groups with different phenotype by focusing on the gene expression should be larger, if a certain gene functional set was significantly associated with a particular phenotype.

Arguments

Details

ll{ Package: DBGSA Type: Package Version: 1.1 Depends: R(>=2.12.2),methods,fdrtool Suggest: ALL Date: 2011-05-17 License: GPL-3 LazyLoad: yes BiocViews: bioinformatics }

References

Lu Tian, Steven A. Greenberg, Sek Won Kong, Josiah Altschuler,Discovering statistically significant pathways in expression profiling studies, PNAS 2005 102;13544-13549