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DEMEtics (version 0.8.0)
Calculation of Gst and D values characterizing the genetic
differentiation between populations.
Description
Out of a table comprising allelic data of at least one
locus for several individuals and from at least two
populations, measurements of genetic differentiation (i.e. D,
Dest, Dest.Chao, Gst and Gst.est (Jost, 2008)) can be
calculated. P-values and 95% confidence intervals are
calculated according to Manly (1997) using a bootstrap method.
Thereby, for each locus, alleles are reallocated over
populations if they are all in Hardy Weinberg Equilibrium
(HWE). If not, the genotypes are reallocated, since alleles can
not be assumed to be inherited independently from each other
(Goudet, 1996). The p-values state how much the empirical found
allocation of alleles over populations differs from an
allocation that could arise by chance alone. In the case that
more than two populations are compared pairwise, the p-values
are adjusted besides using bonferroni correction in several
other ways due to the multiple comparison from one data set.