EWOC.Comb (version 1.0)

Escalation with Overdose Control using 2 Drug Combinations

Description

Implements Escalation With Overdose Control trial designs using two drug combinations described by this paper (Tighiouart et al., 2016). It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.

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Version

Install

install.packages('EWOC.Comb')

Monthly Downloads

196

Version

1.0

License

GPL (>= 2)

Maintainer

Yujie Cui

Last Published

July 18th, 2024

Functions in EWOC.Comb (1.0)

pdlt

Generating probability of DLT based on the EWOC2 model

mtdcurve

Generating MTD curve based on logistic model for two drugs

ewoc2

Escalation With Overdose Control for two drugs combination

EWOC2-internal

Internal functions for EWOC2

print.ewoc2

Summarizing EWOC2 next doses results

plot.ewoc2simu

EWOC for 2 drugs combination trial design characteristics

print.ewoc2simu

Summarizing EWOC2 simulation results

ewoc2simu

Generic EWOC2 simulation

EWOC.Comb-package

tools:::Rd_package_title("EWOC.Comb")